Paddington Station is a central London railway terminus and London Underground complex, located on Praed Street in the Paddington area. The site has been the London terminus of services provided by the Great Western Railway and its successors since 1838.
In 28 Days Later
During the Original Outbreak of the Rage Virus (most likely on Day 15, during the exodus), approximately twenty thousand people including Mark and his family arrived at Paddington Station, hoping to escape the country on a train. However, a few of the people in the crowd were infected, and the Infection quickly spread through the crowd, infecting and killing many of the people except for Mark. (28 Days Later (film))